UK Unveils Plan To Cut Animal Testing Through Greater Use of AI

Animal testing in science would be phased out faster under a new plan to increase the use of artificial intelligence and 3D bioprinted human tissues, a UK minister has said. The Guardian: The roadmap unveiled by the science minister, Patrick Vallance, backs replacing certain animal tests that are still used where necessary to determine the safety of products such as life-saving vaccines and the impact pesticides have on living beings and the environment. The strategy says phasing out the use of animals in science can only happen when reliable and effective alternative methods with the same level of safety for human exposure can replace them.

The government said new funding for researchers and streamlined regulation would help develop methods such as organ-on-a-chip systems -- tiny devices that mimic how human organs work using real human cells. Greater use of AI to analyse vast amounts of data about molecules and predict whether new medicines will be safe and work well on humans would be deployed, while 3D bioprinted tissues could create realistic human tissue samples, from skin to liver, for testing.

Other plans under the strategy include an end to regulatory testing on animals to assess the potential for skin and eye irritation and skin sensitisation by the end of 2026. By 2027, researchers are expected under the strategy to end tests of the strength of botox on mice, while by 2030 pharmacokinetic studies -- which track how a drug moves through the body over time -- on dogs and non-human primates will be reduced.

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