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Surgeons Transplant Genetically Modified Pig Liver Into Chinese Patient
Thursday March 27, 2025. 08:00 AM , from Slashdot
![]() The pig had six genetic modifications aimed at preventing immune rejection. These included deactivating genes that contribute to the production of sugars on the surface of pig cells, which the human immune system attacks, and introducing genes that express human proteins to 'humanize' the liver. After the transplant, the pig liver showed signs of functioning, including producing bile, which helps break down fats in the digestive system, and porcine albumin, a blood protein. The team behind the advance, described in the journal Nature, said it was not clear whether the liver would have been able to fully support the patient, given that he had an existing liver and because the liver was removed after 10 days at the request of his family. Read more of this story at Slashdot.
https://science.slashdot.org/story/25/03/27/0030207/surgeons-transplant-genetically-modified-pig-liv...
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